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Detail Karya Ilmiah Dosen

Tri Saptari Haryani, Bina Lohita Sari , Triastinurmiatiningsih ,Dwi Liana Hanura

Judul : Formulation Of Padina australis Extract Tablet As Antibacterial Escherichia coli
Abstrak :

Padina australis (P.australis) is one of the seaweed that have a potential as antibacterial Escherichia coli (E.coli). Triterpenoids and steroids are secondary metabolites compounds contained in seaweed, and has a variety of activities as bactericide, and hypo-allergenic. This study aims to establish tablet formulation and determine the effectiveness against of E.coli bacteria causing diarrheal disease. The formulation was prepared with these treatment: formula I (20%), formula II (25%), formula III (30%), using a negative control in the form of tablet with no active ingredient, and a positive control using amoxycillin (10 ppm). The formulas’ effectiveness was tested by calculating the inhibition zone width (IZW) –a clear zone resulting from the three formulas, negative, and positive control– using Kirby-Bauer method. The result shows that the formulation with active ingredient of 30% of P. australis extract has an inhibitory activity of 7.7 mm and effective as antibacterial Escherichia coli. Thus it can be concluded that the formulation of 30% of P. australis extract tablet is the most effective formula as antibacterial E. coli causing diarrhea disease.

Keyword: Padina australis, tablets, antibacterial, Escherichia coli.

 

 

 

Tahun : 2018 Media Publikasi : Seminar Internasional
Kategori : Jurnal No/Vol/Tahun : - / - / -
ISSN/ISBN : -
PTN/S : Universitas Pakuan Program Studi : BIOLOGI
Bibliography :

[]  DepKes RI. 1995. Farmakope Indonesia. Edisi keempat. Jakarta: Health Department of Indonesia

[]  Fitrya. 2010. Pemeriksaan Karakteristik Simplisia Alga Padina australis Hauck (Dictyotaceae). Jurnal Penelitian Sains. (September, XIII). No. 3.

[]  Harborne. J. 1987. Metode Fitokimia. Edisi ke-2. Kosasih Padmawinata, penerjemah. Bandung. ITB-Press.

[]  Haryani, Tri Saptari and Triastinurmiatiningsih. 2014. Pengembangan Formula Tablet Ekstrak Padina australis Sebagai  Antibakteri

                   Escherichia coli Penyebab Penyakit Diare. Hasil Penelitian Hibah Fundamental Tahun ke satu, Kemenristek Dikti.

[]  Lachman, L., Lieberman, HA. Kanig J.L. 1989. Teori dan Praktek Farmasi Industri. Edisi ke 3. Penerjemah: Siti Suyatmi.

Jakarta: UI Press.Terjemahan dari: The Teory and Practice of Industrial Pharmacy.

[]  Putra, S. E. 2006. Biota Laut sebagai Biotarget Industri. Laporan Penelitian. Universitas Lampung. Bandar Lampung

(www. energi. lipi.go.id/utama.cgi /artikel 211586897

[]  Rosyidah, K., S.A. Nurmuhaimina, N.Komari, and M.D. Astuti 2010. Aktivitas Antibakteri Fraksi Saponin Dari Kulit Batang

Tumbuhan Kasturi (Mangifera casturi). Alchemy. Vol 1 no 2. Maret 2010.

[]  Santoso    J.    2003.    Studies    on    nutritional components and antioxidant activity in several Indonesia seaweeds [disertasi]. Tokyo:

chemistry of Food and Nutrition Laboratory.  Department of Food science and Technology, Gradyate School of Fisheries: Tokyo University of Fisheries; Matematika Dan Ilmu Pengetahuan Alam, Universitas Padjajaran. Bandung.

[]  Sergiana. 2009. Ganggang Hijau Biru. AgroMedia Pustaka. Jakarta.

[]  Soebagio, B., Rusdiana, T. dand Khairudin. 2007. Pembuatan Gel Dengan Aqupec hv-505 dari Ekstrak Umbi Bawang Merah (Allium cepa,

L.) sebagai Antioksidan. Bandung: Fakultas Farmasi, Universitas Padjajaran.

[]  Syamsuni A. 2006. Ilmu Resep. Penerbit Buku Kedokteran. Jakarta.

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