Leny Heliawati, Agus Kardinan,Tri Mayanti , Roekmi-ati Tjokronegoro

Judul	:	Piceatanol: Anti-Cancer Compound From Gewang Seed Extract
Abstrak	:	Piceatannol (Compound 1), brownish white solids compound, is a stilbene compound has been isolated from methanol seeds extract of Corypha utan Lamk. Isolation and purification conducted by chromatographic methods. Structure elucidation deduced on the basis of spectroscopic data (UV spectrometer, FTIR, NMR and HRMS). MTT assay method of cytotoxicity activity showed that Compound 1 has a very strong cytotoxic activity against Murine leukemia P-388 cell lines with IC50 value 1.56 ppm.
Tahun	:	2015	Media Publikasi	:	Jurnal Internasional
Kategori	:	Jurnal	No/Vol/Tahun	:	1 / 5 / 2015
ISSN/ISBN	:	2231-3354
PTN/S	:	Universitas Pakuan	Program Studi	:	KIMIA
Bibliography	:	Alley, M. C., Scudiero,D. A., Monks,A., Hursey, M. L., Czerwinski, M.J., Fine, D. L., Abbott, B. J., Mayo, J. G., Shoemaker, R. H., and Boyd., M. R. Feasibility of drug screening with panels of tumor cell lines using a microculturetetrazolium assay. Cancer Research 1988;48: 589-601. Brinker, A.M., and Seigler, D.S. Isolation and Identification of Piceatannol as A Phytoalexin from Sugarcane. Phytochemistry, 1991; 30(10). 3229-3232. Carballo, J.L., Hernandez-Inda, Z.L., Perez, P., GarciaGravaloz, M.D. Comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products. BMC Biotechnology, 2002; 2:1472-6570. Gudrun, U.M.D., Panec, H. Zeitle., Vetter and H. Wagner. Drug development from Natural product : Exploiting synergy effect. Indian Journal of Experimental Biology, 2010; 48: 208-209. Hostettman, K. 1991. Assay of bioactivity. Method in plant biochemistry, series editor P. M. Dey, J. B. hardorne, Vol 6, Academic Press, London. Steven, M.C. 1993. Bioactive Natural Product : Detection, isolation, anti Structural Determination, CRC Press.
URL	:	www.japsonline.com/admin/php/uploads/1422_pdf.pdf