Judul | : | ANTIFUNGAL ACTIVITY SARGASSUM CRASSIFOLIUM AND SARGASSUM POLYCYCTUM AGAINST CANDIDA ALBICANS | |||
Abstrak | : | Introduction: Sargassum crassifolium and Sargassum polycystum are brown algae species and contain active compounds such as flavonoids, alkaloids, saponins, phenols, and triterpenoids that act as antibacterial, antiviral and antifungal. Aims of study was to determine antifungal Sargassum crassifolium and Sargassum polycystum against Candida albicans. Methods: Antifungal activity of Sargassum crassifolium and Sargassum polycystum extract were examined using the disc diffusion methods with concentrations of 250 mg/ml and 500 mg/ml compared to Ketoconazole 50 µg/ml against Candida albicans through measurement of the width of the inhibition zone. Qualitative phytochemical tests to know compound of alkaloids, triterpenoid, saponin, flavonoid, and tannin. Results: 500 mg/ml Sargassum crassifolium and Sargassum polycystum exhibited promising fungistatic agent against Candida albicans with diameter of inhibition zone i.e 22 mm for Sargassum crassifolium and 21.6 mm Sargassum polycystum and the its power of the antifungal is lower than Ketoconazole 50 µg/ml. Sargassum crassifolium and Sargassum polycystum contained triterpenoids, saponins, and flavonoids. Conclusion: 96% ethanol extract of Sargassum crassifolium and Sargassum polycystum have antifungal activity of Candida albicans. Antifungal effect Sargassum crassifolium (22 mm) not real different with Sargassum polycystum (21.6 mm) against Candida albicans. |
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Tahun | : | 2018 | Media Publikasi | : | Seminar Internasional |
Kategori | : | Poster | No/Vol/Tahun | : | 1 / 3 / 2018 |
ISSN/ISBN | : | 274/SK-SKP/PP.IAI.IV/2018 | |||
PTN/S | : | Universitas Pakuan | Program Studi | : | BIOLOGI |
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