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Detail Karya Ilmiah Dosen

Oom Komala, Dwi Wahyu Widayat, Muztabadihardja

Judul : Bioactive Compounds and Antibacterial Activity Of Ethanolic Extracts of Curcuma mangga. Val Against Staphylococcus aureus

Abstrak :
Temu mangga (Curcuma mangga) is a medicinal plant as antioxidants because it contains curcuminoids. The compounds bioactive and antibacterial activity from temu mangga had not been widely researched and other scientific information is still limited. This study aimed to examine the antibacterial activity of the Curcuma mangga against pathogenic bacteria Staphylococcus aureus and determine the phytochemical compounds. Antibacterial research conducted by the diffusion method of ethanol extracts against pathogenic bacteria and qualitatively tested for the presence of chemical constituents. The results showed the antibacterial activity against Staphylococcus aureus. The inhibitory wide diameter for S. aureus (30.5 mm) at aconcentration of 8% of ethanol extracts were equal with Amoxicillin 30 µg/mLt. Minimum Inhibitori Concentration was 2% of ethanolic extracts. Phytochemical analysis of the results of the ethanol extract of Curcuma mangga showed varying bioactive compounds consisting of flavonoids, saponins, quinones and steroids were the most prominent. The research results prove that the C. mangga is a good source of antibacterial against S.aureus.

Keywords: Antibacterial, Curcuma mangga, Ethanolic Extracts, Staphylococcus aureus

Tahun : 2016 Media Publikasi : Jurnal Internasional

Kategori : Jurnal No/Vol/Tahun : 6 / 2 / 2016

ISSN/ISBN : 2395-3470

PTN/S : Universitas Pakuan Program Studi : BIOLOGI

Bibliography :
[1] Abas, F., Lajis, N.H., Shaari, K., Israf, D.A., Stanslas, J., Yusuf, U.K. & Raoft, S.M., Alabdane diterpene glucoside from the rhizome of Curcuma mangga, Journal of Natural Products, 68, pp.1090-1093, 2005.

[2] Akinjogunla, O.J., Yah, C.S., Eghafoma, N.O. &Ogbemudia, F.O., Antibacterial activity of leave extracts of Nymphaea lotus (Nymphaeaceae) on Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin resistant Staphylococcus aureus (VRSA) isolated from clinical samples. Annuals of Biological Research, 1(2), pp.174-184, 2010.

[3] Elizabeth, K.M., Antimicrobial activity of Terminalia bellerica Indian, J.Clin.Biochem, 20, pp.150-153, 2005.

[4] Galeotti, F., Barile, E., Curir, P., Dolci, M.& Lanzotti, V., Flavonoids from carnation (Dianthus caryophllus) and their antifungal activity, Phytochemistry Letters, 1, pp.44, 2008.

[5] Harbone, J.B., Phytochemical Method:As Guide to Modern Techniques of Plant Analysis, 3 rd edition, Chapman and Hall, London, pp. 302, 1998.

[6] Jonathan, G.C., Robert, A.B., Steven, G.W. & Noel, L.O., Natural Occuring fish Poisons from Plants, J. Chem. Educ., 81(10), pp. 1457, 2004.

[7] Palombo, E.A.& Semple, S.J., Antibacterial activity of Traditional medicinal plants. J Ethnopharmacol, 77, pp. 151-157, 2001.

[8] Parekh, J.& Chandren, S., In vitro antimicrobial activities of extracts of Launaea procumbens Roxb (Labiateae). Afr. J. Biomed. Res., 9, pp. 89-93.2006.

[9] Renisheya, J.J.M.T., Johnson, M., Mary, U.M. & Arthy, A., Antibacterial activity of ethanolic extracts of selected medicinal plants against human pathogens, Asian Pacific Journal of Tropical Biomedicine, pp.S76-S78, 2011.

[10] Skene, C.D. &Philip, S., Saponin-adjuvanted particulate vaccines for Clinical Use, Method, 40(1), pp.53-59, 2006.

[11] Sri Nurestri, A.M., Guan, S.L., Sok, L.H., Hashim, Y., Norhanom, A.W., Jean-Frederic, F.W.&Syed, A.A.S., Phytochemical and Cytotoxic Investigations of Curcuma mangga Rhizomes. Molecules, 16(6), pp.4539-4548, 2011.

[12] Xu, R., Zhao, W., Xu, J., Shao, B & Qin, G., studies on bioactive saponins from Chinese medicinal plants, AAdvances in Experimental Medicine and Biology, 400 (3), pp 71-82, 1996.

[13] Zamora-Ros, R., Agudo, A., Lujan-Barroso, L., Romieu, I., Ferrari, P. & Knaze V, Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)study, American Journal of Clinical Nutrition, 96(6), pp.1398-1408, 2012.

URL : www.ijseas.com http://ijseas.com/index php/issue-archive-2/volume2/issue-6/#

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Detail Karya Ilmiah Dosen

Oom Komala, Dwi Wahyu Widayat, Muztabadihardja

Judul	:	Bioactive Compounds and Antibacterial Activity Of Ethanolic Extracts of Curcuma mangga. Val Against Staphylococcus aureus
Abstrak	:	Temu mangga (Curcuma mangga) is a medicinal plant as antioxidants because it contains curcuminoids. The compounds bioactive and antibacterial activity from temu mangga had not been widely researched and other scientific information is still limited. This study aimed to examine the antibacterial activity of the Curcuma mangga against pathogenic bacteria Staphylococcus aureus and determine the phytochemical compounds. Antibacterial research conducted by the diffusion method of ethanol extracts against pathogenic bacteria and qualitatively tested for the presence of chemical constituents. The results showed the antibacterial activity against Staphylococcus aureus. The inhibitory wide diameter for S. aureus (30.5 mm) at aconcentration of 8% of ethanol extracts were equal with Amoxicillin 30 µg/mLt. Minimum Inhibitori Concentration was 2% of ethanolic extracts. Phytochemical analysis of the results of the ethanol extract of Curcuma mangga showed varying bioactive compounds consisting of flavonoids, saponins, quinones and steroids were the most prominent. The research results prove that the C. mangga is a good source of antibacterial against S.aureus. Keywords: Antibacterial, Curcuma mangga, Ethanolic Extracts, Staphylococcus aureus
Tahun	:	2016	Media Publikasi	:	Jurnal Internasional
Kategori	:	Jurnal	No/Vol/Tahun	:	6 / 2 / 2016
ISSN/ISBN	:	2395-3470
PTN/S	:	Universitas Pakuan	Program Studi	:	BIOLOGI
Bibliography	:	[1] Abas, F., Lajis, N.H., Shaari, K., Israf, D.A., Stanslas, J., Yusuf, U.K. & Raoft, S.M., Alabdane diterpene glucoside from the rhizome of Curcuma mangga, Journal of Natural Products, 68, pp.1090-1093, 2005. [2] Akinjogunla, O.J., Yah, C.S., Eghafoma, N.O. &Ogbemudia, F.O., Antibacterial activity of leave extracts of Nymphaea lotus (Nymphaeaceae) on Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin resistant Staphylococcus aureus (VRSA) isolated from clinical samples. Annuals of Biological Research, 1(2), pp.174-184, 2010. [3] Elizabeth, K.M., Antimicrobial activity of Terminalia bellerica Indian, J.Clin.Biochem, 20, pp.150-153, 2005. [4] Galeotti, F., Barile, E., Curir, P., Dolci, M.& Lanzotti, V., Flavonoids from carnation (Dianthus caryophllus) and their antifungal activity, Phytochemistry Letters, 1, pp.44, 2008. [5] Harbone, J.B., Phytochemical Method:As Guide to Modern Techniques of Plant Analysis, 3 rd edition, Chapman and Hall, London, pp. 302, 1998. [6] Jonathan, G.C., Robert, A.B., Steven, G.W. & Noel, L.O., Natural Occuring fish Poisons from Plants, J. Chem. Educ., 81(10), pp. 1457, 2004. [7] Palombo, E.A.& Semple, S.J., Antibacterial activity of Traditional medicinal plants. J Ethnopharmacol, 77, pp. 151-157, 2001. [8] Parekh, J.& Chandren, S., In vitro antimicrobial activities of extracts of Launaea procumbens Roxb (Labiateae). Afr. J. Biomed. Res., 9, pp. 89-93.2006. [9] Renisheya, J.J.M.T., Johnson, M., Mary, U.M. & Arthy, A., Antibacterial activity of ethanolic extracts of selected medicinal plants against human pathogens, Asian Pacific Journal of Tropical Biomedicine, pp.S76-S78, 2011. [10] Skene, C.D. &Philip, S., Saponin-adjuvanted particulate vaccines for Clinical Use, Method, 40(1), pp.53-59, 2006. [11] Sri Nurestri, A.M., Guan, S.L., Sok, L.H., Hashim, Y., Norhanom, A.W., Jean-Frederic, F.W.&Syed, A.A.S., Phytochemical and Cytotoxic Investigations of Curcuma mangga Rhizomes. Molecules, 16(6), pp.4539-4548, 2011. [12] Xu, R., Zhao, W., Xu, J., Shao, B & Qin, G., studies on bioactive saponins from Chinese medicinal plants, AAdvances in Experimental Medicine and Biology, 400 (3), pp 71-82, 1996. [13] Zamora-Ros, R., Agudo, A., Lujan-Barroso, L., Romieu, I., Ferrari, P. & Knaze V, Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)study, American Journal of Clinical Nutrition, 96(6), pp.1398-1408, 2012.
URL	:	www.ijseas.com http://ijseas.com/index php/issue-archive-2/volume2/issue-6/#