Emy Oktaviani, Djoko Wahyono, Probosuseno

Judul	:	EVALUASI PENGGUNAAN ANTIDIABETIK ORAL PADA PASIEN DM TIPE 2 DENGAN GANGGUAN FUNGSI GINJAL RAWAT JALAN DI RSUP Dr. SARDJITO YOGYAKARTA, INDONESIA
Abstrak	:	Abstract. Treatment of diabetes mellitus with renal dysfunction required a drug adjustment. Drug adjustment must based on creatinin clearance (CrCl). This study aimed to evaluate of oral antidiabetic on type 2 diabetic patients with renal dysfunction in outpatient department of Dr. Sardjito, Yogyakarta. This study was observational with cross sectional design. Data collection was done retrospectively through patient’s medical records searching and review. The subjects were type 2 diabetic patients with renal dysfunction in outpatient department who met the inclusion criteria. Evaluation of antidiabetic in this study is done by comparing the patient’s dosage regimen obtained with literature. Literature used in this comparison was Drug Information handbook 20th Edition and Handbook of Renal Pharmacotherapy. The result showed that oral antidiabetic with the highest usage, 57 patient (57%) was single type and the lowest usage, 8 patient (8%) was three combination type. Type of oral antidiabetic with the highest usage was acarbose (36%) and metformin (14%). Out of 100 patients, 38 patient (38%) showed appropriate medication, 62 patient (62%) non-appropriate medication. From 149 case of medicine, the appropriate antidiabetic oral was 51,67% and non-appropriate antidiabetic oral was 48,32%. From this study showed that usage of oral antidiabetic without adjustment was still high. Consequently, the possibility of unachieved clinical outcome was greater. Keywords: DM type 2, renal dysfunction, creatinin clearance, oral antidiabetic
Tahun	:	2017	Media Publikasi	:	Prosiding
Kategori	:	Prosiding	No/Vol/Tahun	:	2 / 8 / 2017
ISSN/ISBN	:	978-602-73121-2-8
PTN/S	:	Universitas Pakuan Bogor	Program Studi	:	FARMASI
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