Repository Universitas Pakuan

Detail Karya Ilmiah Dosen

Yatri Hapsari, Eris Septiana, Fauzy Rachman, Syamsiah Syamsiah, Wien Kusharyoto, Leny Heliawati, Bustanussalam Bustanussalam, Siti Irma Rahmawati, Fauzia Nurul Izzati, Partomuan Simanjuntak

Judul : Potensi Aktivitas Antimalaria Dari Ekstrak Air Daun Jung Rahab (Baeckea Frutecens) (Potency of Antimalarial Activity from Aqueaous Extract of Jung Rahab Leaves (Baeckea frutecens)).

Abstrak :
Malaria is a disease caused by Plasmodium parasite transmitted by female Anopheles mosquito. Jung rahab plant (Baeckea frutecens) is known have an ability to inhibit the growth of Plasmodium falciparum. However, the inhibition of the parasite growth is still unknown. This research aimed to determine fractionation of aqueaous extract of jung rahab leaves that is contain antimalaria compound with a potential inhibition activity. Jung rahab plant was extracted using decoctition. The analysis included phytochemical screening, column chromatography fractionation, antimalaria activity, and compound identification by using UV-Vis, FT-IR, and GCMS. Jung rahab aqueous extract fraction resulted a potential antimalaria activity with IC50 105,9 ppm and fractionation result based on UV-Vis, FT-IR, and GCMS as pyrogallol.

Tahun : 2021 Media Publikasi : Jurnal Nasional Blm Akreditasi

Kategori : Jurnal No/Vol/Tahun : 2 / 12 / 2021

ISSN/ISBN : -

PTN/S : universitas pakuan Program Studi : KIMIA

Bibliography :
Agustikawati, N., Andayani, Y., & Suhendra, D. (2017). Uji aktivitas antioksidan dan penapisan fitokimia dari ekstrak daun pakoasi dan kluwih sebagai sumber antioksidan alami. Jurnal Penelitian Pendidikan IPA, 3(2)

.

Caesar, L. K., & Cech, N. B. (2019). Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2. Natural Product Reports, 36(6), 869–888.

Fitrianingsih, S. P. (2010). Aktivitas antiplasmodium ekstrak etanol beberapa tanaman obat terhadap mencit yang diinfeksi Plasmodium berghei. Prosiding SNaPP: Sains, Teknologi, 1(1), 1–13.

Fitriastuti, D., Jumina, & Priatmoko. (2017). Heme polymerization inhibition activity (HPIA) assay of synthesized xanthone derivative as antimalarial compound. AIP Conference Proceedings, 1823(1), 20120.

Hapsari, Y., Mahayoga, G. A., Kusharyoto, W., & Simanjuntak, P. (2019). Aktivitas antimalaria berbasis penghambatan $β$-hematin dalam ekstrak air daun jung rahab (Baeckea frutecens L). Chimica et Natura Acta, 7(1), 46–50.

Huy, N. T., Uyen, D. T., Maeda, A., Trang, D. T. X., Oida, T., Harada, S., & Kamei, K. (2007). Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds. Antimicrobial Agents and Chemotherapy, 51(1), 350–353.

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Detail Karya Ilmiah Dosen

Yatri Hapsari, Eris Septiana, Fauzy Rachman, Syamsiah Syamsiah, Wien Kusharyoto, Leny Heliawati, Bustanussalam Bustanussalam, Siti Irma Rahmawati, Fauzia Nurul Izzati, Partomuan Simanjuntak

Judul	:	Potensi Aktivitas Antimalaria Dari Ekstrak Air Daun Jung Rahab (Baeckea Frutecens) (Potency of Antimalarial Activity from Aqueaous Extract of Jung Rahab Leaves (Baeckea frutecens)).
Abstrak	:	Malaria is a disease caused by Plasmodium parasite transmitted by female Anopheles mosquito. Jung rahab plant (Baeckea frutecens) is known have an ability to inhibit the growth of Plasmodium falciparum. However, the inhibition of the parasite growth is still unknown. This research aimed to determine fractionation of aqueaous extract of jung rahab leaves that is contain antimalaria compound with a potential inhibition activity. Jung rahab plant was extracted using decoctition. The analysis included phytochemical screening, column chromatography fractionation, antimalaria activity, and compound identification by using UV-Vis, FT-IR, and GCMS. Jung rahab aqueous extract fraction resulted a potential antimalaria activity with IC50 105,9 ppm and fractionation result based on UV-Vis, FT-IR, and GCMS as pyrogallol.
Tahun	:	2021	Media Publikasi	:	Jurnal Nasional Blm Akreditasi
Kategori	:	Jurnal	No/Vol/Tahun	:	2 / 12 / 2021
ISSN/ISBN	:	-
PTN/S	:	universitas pakuan	Program Studi	:	KIMIA
Bibliography	:	Agustikawati, N., Andayani, Y., & Suhendra, D. (2017). Uji aktivitas antioksidan dan penapisan fitokimia dari ekstrak daun pakoasi dan kluwih sebagai sumber antioksidan alami. Jurnal Penelitian Pendidikan IPA, 3(2) . Caesar, L. K., & Cech, N. B. (2019). Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2. Natural Product Reports, 36(6), 869–888. Fitrianingsih, S. P. (2010). Aktivitas antiplasmodium ekstrak etanol beberapa tanaman obat terhadap mencit yang diinfeksi Plasmodium berghei. Prosiding SNaPP: Sains, Teknologi, 1(1), 1–13. Fitriastuti, D., Jumina, & Priatmoko. (2017). Heme polymerization inhibition activity (HPIA) assay of synthesized xanthone derivative as antimalarial compound. AIP Conference Proceedings, 1823(1), 20120. Hapsari, Y., Mahayoga, G. A., Kusharyoto, W., & Simanjuntak, P. (2019). Aktivitas antimalaria berbasis penghambatan $β$-hematin dalam ekstrak air daun jung rahab (Baeckea frutecens L). Chimica et Natura Acta, 7(1), 46–50. Huy, N. T., Uyen, D. T., Maeda, A., Trang, D. T. X., Oida, T., Harada, S., & Kamei, K. (2007). Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds. Antimicrobial Agents and Chemotherapy, 51(1), 350–353.
URL	: