Repository Universitas Pakuan

Detail Karya Ilmiah Dosen

Prasetyorini, Moerfiah, Zaldy Rusli

Judul : Potensi Antioksidan Berbagai Sediaan Buah Sirsak (Annona muricata Linn) [Potential Test of Antioxidant Various Preparation of Soursop Fruit (Annona muricata Linn)

Abstrak :
Soursop is a potential source of antioxidant due to high vitamin C and poliphenol content. Antioxidant activity of three different preparations i.e. fruit juice, 96% ethanol extract, and ethyl acetate extract. The antiocdidant were measured by using 1.1-diphenyl-2 pycrihidrazyl (DPPH) radical solution. In addition, vitamin C and polyphenol content of each preparation were also measured. Polyphenol content as measured in gram Gallic Acid Equivalent (GAE)/100 g). Showed the fruit juice, 96% ethanol extract and ethyl acetate extract were 0,473, 0,324, and 0,194, respectively. Vitamin C content (mg/100 g) of these three preparations were 36.24, 30.56, and 35.66, respectively. The antioxidant activities (ppm) determined by IC50 showed fruit juice, 96% ethanol extract and ethyl acetate extract were 282.61 ppm, 660.08 and 480.26, respectively. There was strong correlation between vitamin C content and antioxidant activity, and between polyphenol content and antioxidant activities. In conclusion, the use of fruit juice as antioxidant source was better than ethyl acetate and ethanol 96% extract.

Tahun : 2014 Media Publikasi : jurnal nasional terakreditasi A

Kategori : Jurnal No/Vol/Tahun : 2 / 37 / 2014

ISSN/ISBN : 0125-9717

PTN/S : Universitas Pakuan Program Studi : FARMASI

Bibliography :

Astawan M. Awet muda berkat sirsak. 2010 [sitasi: 9 Oktober 2012]. Dalam: http://health.kompas.com/read/2010/03/18 /09094978/Awet.Muda.Berkat.Sirsak.

Thomas.Tanaman obat tradisional, edisi 2. Yogyakarta: Kanisius, 1992.

Taylor L. Herbal secrets of the rainforest. 2nd ed. New York: Sage Press, 2002.

Winarsi H. Antioksidan alami dan radikal bebas. Yogyakarta: Kanisius, 2007.

Kikuzaki H, Hisamoto M, Hirose K, Akiyama K, and Taniguchi H. Antioxidants properties of ferulic acid and its related compound. J Agric Food Chem. 2002;50: 2161-8.

Halliwall. Reactive species and antioxidant, redox biology is a fundamental theme for aerobic life. Plant Physiol. 2006;141:312-322.

Bora PS, Holschuh HJ, dan Vasconcelos MAS. Characterization of polyphenol oxidase of soursop (Annona muricata L.) fruit and comparative study of its inhibition in enzyme extract and in pulp. Cienciay Tecnologia Alimentaria. 2004;4:267-273.

Radi J. Sirsak, budidaya dan peman-faatannya. Yogyakarta:Kanisius,1997

Dawidowicz AL, and Olszowy M. Mechanism change in estimating of antioxidant activity of phenolic compounds.Talanta. 2012:97;312-317.

Marinna E, Georgiew L, Totsera I, Seizova K, and Milkova T. Antioxidant activity and mechanism of action of some synthesized phenolic acid amides of aromatic amines. Czech J Food Sci. 2013;31:5-13

Kao MWS, FM Woods, WA Dozier, RC Ebet, M Nesbitt, J Jee, et al. Phenolic content and antioxidant capacities of Alabama-Grown thornless blackber-ries. Int J Fruit Sci. 2008;7:33-46.

Stanojevic L, Stankovich M, Nikolic V, Nikolic L, Ristic D, Brunet JC et.al. Antioxidant activity, total phenolic and flavonoid content of Hieracium picosella L extract. Sensors. 2009;9:5702-5714.

Haciseuki A. An overview of ascorbic acid biochemistry. J Fac Pharm Ankara. 2009;38:233-255.

Wanasundara PKJPD, Shahidi F, editors. Antioxidants: science, technology, and application. New Jersey: John Wiley & Sons, 2005.

Huang DJ, Ou BX, and Prior RL. The chemistry behind antioxidant capacity assay. J Agric Food Chem. 2005;53:1841-1856.

Rajendra CE, Magadum DS, Nadaf MA, Yoshada SV, Manjula M. Phytochemical screening of the rhizome of kaempferia galanga. Int J Pharm and Phyto Research.2011;3:61-63.

Gonzalez M, Guzman B, Rudyk R, Romana E, and Molina MAA, Spectrophotometric determination of phenolic coumpounds in propolis. Lat Am J Pharm.2003;22:243-8.

Dioha IJ, O Olugbemi, TU Onuegbu and Z Shahru. Determination of ascorbic acid content of some tropical fruits by iodometric titration. Int J Biol Chem Sci. 2011;5:2180-2184.

Harmita. Buku ajar analisis fisikokimia. Jakarta: Cipta Kreasi Bersama, 2006.

Molyneux P. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity.Songklanarin J Sci Technol. 2004;26: 211-219.

Yen GC and Chen HY. Antioxidant activity of carius tea extract in relation to their antimutangeneticity. J Agri and Food Chem.1995;43:27-32.

Jonathan S. Statistik itu mudah: panduan lengkap untuk belajar komputasi statistik menggunakan SPSS 16. Yogyakarta: Universitas Atmajaya, 2009.

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Detail Karya Ilmiah Dosen

Prasetyorini, Moerfiah, Zaldy Rusli

Judul	:	Potensi Antioksidan Berbagai Sediaan Buah Sirsak (Annona muricata Linn) [Potential Test of Antioxidant Various Preparation of Soursop Fruit (Annona muricata Linn)
Abstrak	:	Soursop is a potential source of antioxidant due to high vitamin C and poliphenol content. Antioxidant activity of three different preparations i.e. fruit juice, 96% ethanol extract, and ethyl acetate extract. The antiocdidant were measured by using 1.1-diphenyl-2 pycrihidrazyl (DPPH) radical solution. In addition, vitamin C and polyphenol content of each preparation were also measured. Polyphenol content as measured in gram Gallic Acid Equivalent (GAE)/100 g). Showed the fruit juice, 96% ethanol extract and ethyl acetate extract were 0,473, 0,324, and 0,194, respectively. Vitamin C content (mg/100 g) of these three preparations were 36.24, 30.56, and 35.66, respectively. The antioxidant activities (ppm) determined by IC50 showed fruit juice, 96% ethanol extract and ethyl acetate extract were 282.61 ppm, 660.08 and 480.26, respectively. There was strong correlation between vitamin C content and antioxidant activity, and between polyphenol content and antioxidant activities. In conclusion, the use of fruit juice as antioxidant source was better than ethyl acetate and ethanol 96% extract.
Tahun	:	2014	Media Publikasi	:	jurnal nasional terakreditasi A
Kategori	:	Jurnal	No/Vol/Tahun	:	2 / 37 / 2014
ISSN/ISBN	:	0125-9717
PTN/S	:	Universitas Pakuan	Program Studi	:	FARMASI
Bibliography	:	Astawan M. Awet muda berkat sirsak. 2010 [sitasi: 9 Oktober 2012]. Dalam: http://health.kompas.com/read/2010/03/18 /09094978/Awet.Muda.Berkat.Sirsak. Thomas.Tanaman obat tradisional, edisi 2. Yogyakarta: Kanisius, 1992. Taylor L. Herbal secrets of the rainforest. 2nd ed. New York: Sage Press, 2002. Winarsi H. Antioksidan alami dan radikal bebas. Yogyakarta: Kanisius, 2007. Kikuzaki H, Hisamoto M, Hirose K, Akiyama K, and Taniguchi H. Antioxidants properties of ferulic acid and its related compound. J Agric Food Chem. 2002;50: 2161-8. Halliwall. Reactive species and antioxidant, redox biology is a fundamental theme for aerobic life. Plant Physiol. 2006;141:312-322. Bora PS, Holschuh HJ, dan Vasconcelos MAS. Characterization of polyphenol oxidase of soursop (Annona muricata L.) fruit and comparative study of its inhibition in enzyme extract and in pulp. Cienciay Tecnologia Alimentaria. 2004;4:267-273. Radi J. Sirsak, budidaya dan peman-faatannya. Yogyakarta:Kanisius,1997 Dawidowicz AL, and Olszowy M. Mechanism change in estimating of antioxidant activity of phenolic compounds.Talanta. 2012:97;312-317. Marinna E, Georgiew L, Totsera I, Seizova K, and Milkova T. Antioxidant activity and mechanism of action of some synthesized phenolic acid amides of aromatic amines. Czech J Food Sci. 2013;31:5-13 Kao MWS, FM Woods, WA Dozier, RC Ebet, M Nesbitt, J Jee, et al. Phenolic content and antioxidant capacities of Alabama-Grown thornless blackber-ries. Int J Fruit Sci. 2008;7:33-46. Stanojevic L, Stankovich M, Nikolic V, Nikolic L, Ristic D, Brunet JC et.al. Antioxidant activity, total phenolic and flavonoid content of Hieracium picosella L extract. Sensors. 2009;9:5702-5714. Haciseuki A. An overview of ascorbic acid biochemistry. J Fac Pharm Ankara. 2009;38:233-255. Wanasundara PKJPD, Shahidi F, editors. Antioxidants: science, technology, and application. New Jersey: John Wiley & Sons, 2005. Huang DJ, Ou BX, and Prior RL. The chemistry behind antioxidant capacity assay. J Agric Food Chem. 2005;53:1841-1856. Rajendra CE, Magadum DS, Nadaf MA, Yoshada SV, Manjula M. Phytochemical screening of the rhizome of kaempferia galanga. Int J Pharm and Phyto Research.2011;3:61-63. Gonzalez M, Guzman B, Rudyk R, Romana E, and Molina MAA, Spectrophotometric determination of phenolic coumpounds in propolis. Lat Am J Pharm.2003;22:243-8. Dioha IJ, O Olugbemi, TU Onuegbu and Z Shahru. Determination of ascorbic acid content of some tropical fruits by iodometric titration. Int J Biol Chem Sci. 2011;5:2180-2184. Harmita. Buku ajar analisis fisikokimia. Jakarta: Cipta Kreasi Bersama, 2006. Molyneux P. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity.Songklanarin J Sci Technol. 2004;26: 211-219. Yen GC and Chen HY. Antioxidant activity of carius tea extract in relation to their antimutangeneticity. J Agri and Food Chem.1995;43:27-32. Jonathan S. Statistik itu mudah: panduan lengkap untuk belajar komputasi statistik menggunakan SPSS 16. Yogyakarta: Universitas Atmajaya, 2009.
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