Repository Universitas Pakuan

Detail Karya Ilmiah Dosen

Sri Wardatun, Erni Rustiani, Nella Alfiani, Desta Rissani

Judul : Study Effect Type of Extraction Method And Type of Solvent To Cinnamaldehyde and Trans-Cinnamic Acid Dry Extract Cinnamon (Cinnamomum burmanii [Nees & T, Nees]Blume)
Abstrak :

Introduction: We  report  the  effects of extraction methods  and  the  type  of solvent to  cinnamaldehyde and  trans-cinnamic acid content of dry extract of cinnamon (Cinnamomum  burmanii  [Nees   & T,Nees]   Blume).  Methods: The extraction method used  maceration, soxhletation and  infundation. We  used

50%,  70%  and  96%  ethanol as  solvent, while  for methods  infundation used aquadest. Liquid extract dried to obtain dry extract. Cinnamaldehyde and trans- cinnamic  acid  measured by spectrophotometric UV-Visibel. Results: The  re- sults  of the  assays showed that  method of maceration with 96%  ethanol had cinnamaldehyde content on 124.14 ± 1.17 mg/g dry extract and trans-cinnamic acid  content on  151.35 ±  1.24  mg/g  dry extract. Statistical test showed that method of extraction and  type  of solvent had  a significant  effect of cinnamal- dehyde and trans-cinnamic acid contents. Conclusion: 96%  Ethanol  and 70% ethanol solvent had a significant  effect of cinnamaldehyde and trans-cinnamic

 

 

 

acid contents, while  50%  ethanol and  aquadest hadn’t  a significant  effect of cinnamaldehyde and trans-cinnamic acid contents.

Key words: Dry extract cinnamon, Cinnamaldehyde, Trans-cinnamic acid.

Tahun : 2017 Media Publikasi : Jurnal Internasional
Kategori : Jurnal No/Vol/Tahun : 1 / 9 / 2017
ISSN/ISBN : 0975-1505
PTN/S : UNPAK Program Studi : FARMASI
Bibliography :

1.  Allen RW, Schwartzman E, Baker WL, Coleman CI, Phung  OJ.  Cinnamon use in type  2 diabetes: an updated systematic review  and meta-analysis. Ann Fam Med.  2013;11(5):452-9.

2.  Cao H, Polansky  MM, Anderson RA. Cinnamon extract and polyphenols affect the  expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes. Arch Biochem Biophys.  2007;459(2):214-22.

3.  Utchariyakiat  I, Surassmo S,  Jaturanpinyo M,  Khurtayaporn P,  Chomnawang

 

 

MT. Efficacy of Cinnamon bark oil and cinnamaldehyde on anti multidrug  resis- tant  Pseudomonas aeruginosa and  the  synergistic effect in combination with other   antimicrobial   agent. BMC  Complementary  and  Alternative   Medicine.

2016;16(158):2-7

4.  Rana  IS, Singh  A, Gwal  R. In vitro study  of antibacterial activity  of aromatic and medicinal  plant.  essensial oil with spesial reference of cinnamol  oil. Inter- national  Journal of Pharmacy and Pharmaceutical Sciences. 2011;3(4):376-80.

5.  Zinn S, Betz T, Medcraft C, Schnell  M. Structure determination on  trans  cin- namaldehyde by broadband microwave spectroscopy. Phys Chem  Chem  Phys.

2015;17:16080-5

6.  Sharma P. Cinnamic acid derivatives: a new  chapter of various  pharmacological activities. J Chem  Pharm  Res.  2011;3(2):403-23

7.  Aprianto.  Ekstraksi  cinnamaldehyde dan  oleoresin dari  kayu  manis  berbantu ultrasonik.  Master Thesis, Faculty  of Chemistry Engineering, University  of Di- ponegoro Semarang, Central of Java, Indonesia. 2011.

8.  Araar H. Cinnamon plant extracts: a comprehensive physico-chemical and bio- logical study  for its potential use  as  a biopesticide. Master of Science. MSc. Thesis, Mediterranean Organic Agriculture. Instituto Agronomico Mediterraneo, Bari. 2009

9.  Rind FMA, Memon AH, Almani F, Laghari MGH, Mughal  UR, Maheshwari  ML, et  al. Spectrophotometric determination of cinnamaldehyde from crude  drugs and herbal  preparations. Asian Journal of Chemistry. 2011;23(2):631-5.

10.  Gursale  A, Dighe V, Parekh  G. Simultaneus quantitative determination of cin- namaldehyde and  methyl  eugenol from  stem bark of Cinnamomum zeylicum Blume using RP-HPLC. Journal of Chromatographic Science. 2010;48(1):59-62

11.  Lee  J, Lee  DG, Park JY, Chae  SW, Lee  S. Analysis  of the  trans  cinnamic  acid content in cinnamomum spp and commercial of cinnamon powder using HPLC. Journal of Agricultural Chemistry and Enviromnent. 2015;4(4):102-108.

12.  Truong VT. Effect  of cinnamic  acid-cyclodextrin inclusion  complexes on popula- tions of Escherichia coli O157:H7  and Salmonella entericain Fruit Juices. M.Sc. Thesis, Faculty  of the  Virginia Polytechnic Institute and  State University,  Vir- ginia. 2007.

13.  Clark GS. An Aroma  Chemical  Profile,  CinnamicAldehyde,CommoditySevices

International Inc., Maryland.  1991.

URL :

 

Document

 
back