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Detail Karya Ilmiah Dosen

Oom Komala, Sri Wardatun, Lia Puspita Sari3

Judul : Effectiveness of Leaves Extract Fractions of Archidendron jiringa (Jack) I.C Nielsen Against Microbes
Abstrak :

Archidendron jiringa (Jack) I.C Nielsen) contains a lot of essential oils, saponins, alkaloids, terpenoids, steroids, tannins, glycosides, and flavonoids. Flavonoid is a secondary metabolite compound in a plant as antimicrobial. This study aims to determine the antimicrobial activity of fractions of ethanol 96% , n-hexan , ethyl acetate , and ethanol-water leaves extract.  A. jiringa leaves extract were tested against Streptococus mutans, Pseudomonas aeruginosa, and Candida albicans.  The research using agar disc diffusion technique for antimicrobial  activity and colorimetric method to know the total of flavonoid. Chloramphenicol and ketoconazole were used as a reference standard.  The result of this study shows fractions of ethanol 96% ,  n-hexane ,  ethyl acetate , and  ethanol-water  A. jiringa leaves extract  can inhibit microbial growth of S. mutans, P. aeruginosa, and C. albicans. Total of flavonoids on the extract respectively are 1,13%, 0,494%, 2,337%, and 0,549%.   The higher  percent of flavonoids would cause greater    inhibitory  zone  bacteria but  only  0.090  for  pearson correlation value. Conclusions ethyl acetate leaves extract most effective inhibit microbial growth from the other fractions.

Tahun : 2020 Media Publikasi : Jurnal Internasional
Kategori : Jurnal No/Vol/Tahun : 2 / 14 / 2019
ISSN/ISBN : 1907-9761
PTN/S : Universitas Pakuan Program Studi : BIOLOGI
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