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Sri Wardatus, Sutanto, Euis Mahmudah

Judul : Effect Type of Solvent for Extraction Binahong Leaves (Anrederacordifolia (Ten.) Steenis) on Saponin Levels by Gravimetric Method

Abstrak :
Effect Type of Solvent for Extraction Binahong Leaves (Anrederacordifolia (Ten.) Steenis) on Saponin Levels by Gravimetric Method
Sri Wardatun, Sutanto, Euis Mahmudah

Abstract:

Secondary metabolites, also known as phytochemicals, natural products or plant constituents are responsible for medicinal properties of plants. The Secondary metabolite compounds contained in binahong leaves were steroids, alkaloids, flavonoids, saponins, polyphenols and tannins. The purpose of this research was for determine the content of saponin compounds in binahong leaves extract by gravimetric method with differents type of solvent. Binahong leaves made into simplicia and extracted using 3 types of solvents: 70% ethanol, 95% ethanol and methanol. The extraction was performed in reflux. The extract fractionated with n-hexane, ethyl acetate and n-butanol solvent, respectively.
The levels of saponin in fraction n-butanol determined by gravimetric methods. The results showed that the type of solvent had an effect on the levels of isolated saponins. The methanol solvent produced the highest saponins in 54.30%, 95% ethanol in 35.84% and 70% ethanol in 25.91%, respectively.

Index Terms: Binahong leaves, Saponins, Methanol, 70% ethanol, 95% ethanol.

Tahun : 2019 Media Publikasi : Jurnal Nasional Blm Akreditasi

Kategori : Jurnal No/Vol/Tahun : International Journal of Recent Technology and Engineering (IJRTE), / 8 / 2019

ISSN/ISBN : ISSN: 2277-3878,

PTN/S : Universitas Pakuan Program Studi : KIMIA

Bibliography :

REFERENCES

1. B. Elya, R. Handayani, R. Sauriasari, R., Azizahwati, U. S. Hasyyati, I. T.Permana and Y. I. Permatasari. “Antidiabetic activity and hytochemical screening of extracts from indonesian plants by inhibition of alpha amylase, alpha glucosidase and dipeptidyl peptidase IV.” Pakistan Journal of Biological Sciences, vol. 18, no. 6, pp. 273–278, 2015.

2. E. Moghimipour and S. Handali. “Saponin: Properties, Methods of Evaluation and Applications.” Annual Research & Review in Biology, vol. 5, no. 3, pp. 207–220, 2015.

3. R. A. V. I. Lokesh, V. Manasvi and B, P. Lakshmi. “Antibacterial and Antioxidant Activity of Saponin From Abutilon Indicum Leaves.” Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 9, pp. 344-347, 2016.

4. R. B. Konri, S. Samaddar and C. T. Ramaiah. Antidiabetic activity of a triterpenoid saponin isolated from Momordica cymbalaria Fenzl. Indian Journal of Experimental Biology, vol. 52, no. 1, pp. 46–52, 2014.

5. A. Smith. “In Vitro and in Vivo Antioxidant Activity of Saponin Extracted From the Root of Garcinia Kola ( Bitter Kola ) on Alloxan-Induced Diabetic Rats.” World Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, no.7, pp. 8–26, 2014..

6. E. Moghimipour, B. Sadaghi-Nejad, S. Handali, A. Ameri, Z. Ramezani and M. E. Azemi. “In vitro screening of anti-Candida activity of saponins extracted from Glycyrrhiza glabra and Quillaja saponaria.” Asian Journal of Pharmaceutical and Clinical Research, vol. 7, no. 1, pp. 160–162, 2014.

7. S. Odeyemi, A. Afolayan and G. Bradley. “In Vitro Anti-Inflammatory And Free Radical Scavenging Activities Of Crude.” African Journal of Traditional, Complementary, and Alternative Medicines, vol. 12, no. 4, pp 34–40, 2014.

8. A. Soni, P. Femida and P. Sharma. “In-vitro cytotoxic activity of plant saponin extracts on breast cancer cell-line.” Research Journal of Pharmacognosy and Phytochemistry, vol. 9, no. 1, 17-22, 2017.

9. Y. P. Naveen and A. Urooj. “Pharmaceutical research”. Asian Journal of Pharmaceutical Research, vol. 5, no. 3, pp. 161–166, 2015.

10. B. Zhao, W. Zhao and Z. Yuan. “Optimization of extraction method for total saponins from Codonopsis lanceolata.” Asian Journal of Traditional Medicines, vol. 7, no. 1, pp. 14–17, 2012.

11. H. Pham, V. Nguyen, Q. Vuong, M. Bowyer and C. Scarlett. “Effect of Extraction Solvents and Drying Methods on the Physicochemical and Antioxidant Properties of Helicteres hirsuta Lour. Leaves.” Technologies, vol. 3, no. 4, pp. 285–301, 2015.

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Detail Karya Ilmiah Dosen

Sri Wardatus, Sutanto, Euis Mahmudah

Judul	:	Effect Type of Solvent for Extraction Binahong Leaves (Anrederacordifolia (Ten.) Steenis) on Saponin Levels by Gravimetric Method
Abstrak	:	Effect Type of Solvent for Extraction Binahong Leaves (Anrederacordifolia (Ten.) Steenis) on Saponin Levels by Gravimetric Method Sri Wardatun, Sutanto, Euis Mahmudah Abstract: Secondary metabolites, also known as phytochemicals, natural products or plant constituents are responsible for medicinal properties of plants. The Secondary metabolite compounds contained in binahong leaves were steroids, alkaloids, flavonoids, saponins, polyphenols and tannins. The purpose of this research was for determine the content of saponin compounds in binahong leaves extract by gravimetric method with differents type of solvent. Binahong leaves made into simplicia and extracted using 3 types of solvents: 70% ethanol, 95% ethanol and methanol. The extraction was performed in reflux. The extract fractionated with n-hexane, ethyl acetate and n-butanol solvent, respectively. The levels of saponin in fraction n-butanol determined by gravimetric methods. The results showed that the type of solvent had an effect on the levels of isolated saponins. The methanol solvent produced the highest saponins in 54.30%, 95% ethanol in 35.84% and 70% ethanol in 25.91%, respectively. Index Terms: Binahong leaves, Saponins, Methanol, 70% ethanol, 95% ethanol.
Tahun	:	2019	Media Publikasi	:	Jurnal Nasional Blm Akreditasi
Kategori	:	Jurnal	No/Vol/Tahun	:	International Journal of Recent Technology and Engineering (IJRTE), / 8 / 2019
ISSN/ISBN	:	ISSN: 2277-3878,
PTN/S	:	Universitas Pakuan	Program Studi	:	KIMIA
Bibliography	:	REFERENCES 1. B. Elya, R. Handayani, R. Sauriasari, R., Azizahwati, U. S. Hasyyati, I. T.Permana and Y. I. Permatasari. “Antidiabetic activity and hytochemical screening of extracts from indonesian plants by inhibition of alpha amylase, alpha glucosidase and dipeptidyl peptidase IV.” Pakistan Journal of Biological Sciences, vol. 18, no. 6, pp. 273–278, 2015. 2. E. Moghimipour and S. Handali. “Saponin: Properties, Methods of Evaluation and Applications.” Annual Research & Review in Biology, vol. 5, no. 3, pp. 207–220, 2015. 3. R. A. V. I. Lokesh, V. Manasvi and B, P. Lakshmi. “Antibacterial and Antioxidant Activity of Saponin From Abutilon Indicum Leaves.” Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 9, pp. 344-347, 2016. 4. R. B. Konri, S. Samaddar and C. T. Ramaiah. Antidiabetic activity of a triterpenoid saponin isolated from Momordica cymbalaria Fenzl. Indian Journal of Experimental Biology, vol. 52, no. 1, pp. 46–52, 2014. 5. A. Smith. “In Vitro and in Vivo Antioxidant Activity of Saponin Extracted From the Root of Garcinia Kola ( Bitter Kola ) on Alloxan-Induced Diabetic Rats.” World Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, no.7, pp. 8–26, 2014.. 6. E. Moghimipour, B. Sadaghi-Nejad, S. Handali, A. Ameri, Z. Ramezani and M. E. Azemi. “In vitro screening of anti-Candida activity of saponins extracted from Glycyrrhiza glabra and Quillaja saponaria.” Asian Journal of Pharmaceutical and Clinical Research, vol. 7, no. 1, pp. 160–162, 2014. 7. S. Odeyemi, A. Afolayan and G. Bradley. “In Vitro Anti-Inflammatory And Free Radical Scavenging Activities Of Crude.” African Journal of Traditional, Complementary, and Alternative Medicines, vol. 12, no. 4, pp 34–40, 2014. 8. A. Soni, P. Femida and P. Sharma. “In-vitro cytotoxic activity of plant saponin extracts on breast cancer cell-line.” Research Journal of Pharmacognosy and Phytochemistry, vol. 9, no. 1, 17-22, 2017. 9. Y. P. Naveen and A. Urooj. “Pharmaceutical research”. Asian Journal of Pharmaceutical Research, vol. 5, no. 3, pp. 161–166, 2015. 10. B. Zhao, W. Zhao and Z. Yuan. “Optimization of extraction method for total saponins from Codonopsis lanceolata.” Asian Journal of Traditional Medicines, vol. 7, no. 1, pp. 14–17, 2012. 11. H. Pham, V. Nguyen, Q. Vuong, M. Bowyer and C. Scarlett. “Effect of Extraction Solvents and Drying Methods on the Physicochemical and Antioxidant Properties of Helicteres hirsuta Lour. Leaves.” Technologies, vol. 3, no. 4, pp. 285–301, 2015.
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