Repository Universitas Pakuan

Detail Karya Ilmiah Dosen

Emy Oktaviani, Oktaviana Zunnita, Marlia Handayani

Judul : EFEK EDUKASI MELALUI BROSUR TERHADAP KONTROL TEKANAN DARAH DAN KEPATUHAN PASIEN HIPERTENSI

Abstrak :
Adherence is one of the main supporting factors of achieving the therapeutic effect of hypertension treatment. Non-adherence can increase morbidity, mortality, and treatment costs. This study aims to determine the effect of education through brochures on blood pressure control and medication adherence to hypertension. The design of this study is a quasi experimental one group pretest and posttest design prospectively. This study was conducted using respondents of hypertension patients at the Babakan Madang Community Health Center which met the inclusion criteria. Pretest and posttest data collection using MMAS-8 questionnaire and patient medical records. People who are willing to take part in this study are marked by informed consent. The study was conducted by filling out the MMAS-8 questionnaire by interview, blood pressure, and Fitofarmaka Jurnal Ilmiah Farmasi 66 continued with an intervention in the form of education through a brochure. One month later the MMAS-8 questionnaire was filled out with re-interviews and blood pressure measurements. From 50 respondents showed that education through the brochure had an effect on blood pressure control and respondent compliance with the results of statistical tests using the Wilcoxon Signed Rank Test (p<0,05). Keywords: Adherence, blood pressure, brochure, hypertension

Tahun : 2020 Media Publikasi : Jurnal Nasional Terakreditasi A

Kategori : Jurnal No/Vol/Tahun : 1 / 10 / 2020

ISSN/ISBN : 2622-755X

PTN/S : Universitas Pakuan Program Studi : FARMASI

Bibliography :
Ayodapo, A., Elegbede O., Omosanya, O & Monsudi K. 2020. Patient education and medication adherence among hypertensives in a tertiary hospital, South Western Nigeria. Ethiop J Health Sci, 30: 243-250. https://doi.org/10.4314/ejhs.v30i2.1 2. Bijani, M., Tehranineshat B., Ahrari F & Beygi N. 2020. A Comparison between Multimedia and traditional education in encouraging adherence to treatment regimen in patients with hypertension. The Open Hypertention Journal, 12: 1-6. https://doi.org/10.2174/1876526202 012010001. Burnier, M. 2017. Drug adherence in hypertension. Pharmacological Research, 125: 142-149. https://doi.org/10.1016/j.phrs.2017. 08.015. Dewanti, S.W., Andrajati R & Supardi S. 2015. Pengaruh konseling dan leaflet terhadap efikasi diri, kepatuhan minum obat, dan tekanan darah pasien hipertensi di dua puskesmas Kota Depok. Jurnal Kefarmasian Indonesia, 5: 33-40. Egan, B.M., Bandyopadhyay D., Shaftman S.R., Wagner C.S., Zhao Y & Yu-Isenberg K.S. 2012. Initial monotherapy and combination therapy and hypertension control the first year. Hypertension, 59: 1124-1131. https://doi.org/10.1161/HYPERTEN SIONAHA.112.194167. Gaffari-fam, S., Babazadeh T., Oliaei S., Behboodi L & Daemi A. 2020. Adherence to a health literacy and healthy lifestyle with improved blood pressure control in Iran. Patient Prefer Adherence, 14: 499- 506. https://doi.org/10.2147/PPA.S2448 20. Gaziano, T.A., Bertram M., Tollman S.M & Hofman K.J. 2014. Hypertension education and adherence in South Africa: a cost-effectiveness analysis of community health workers. BMC Public Health 14, 240. https://doi.org/10.1186/1471-2458- 14-240. Gellad, W.F., Grenard J.L & Marcum Z.A. 2011. A Systematic Review of Barriers to Medication Adherence in the Elderly: Looking Beyond Cost and Regimen Complexity. The American Journal of Geriatric Pharmacotherapy 9, 11–23. https://doi.org/10.1016/j.amjopharm .2011.02.004. Hill, M.N., Miller N.H & DeGeest S. 2011a. Adherence and persistence with taking medication to control high blood pressure. Journal of the American Society of Hypertension 5, 56–63. https://doi.org/10.1016/j.jash.2011. 01.001. Hill, M.N., Miller N.H. & DeGeest S. 2011b. Adherence and persistence Fitofarmaka Jurnal Ilmiah Farmasi 74 with taking medication to control high blood pressure. Journal of the American Society of Hypertension, 5, 56–63. https://doi.org/10.1016/j.jash.2011. 01.001. Hsiao, F.C., Tung Y.C., Chou S.H., Wu L.S., Lin C.P., Wang C.L., Lin Y.S., Chang C.J & Chu P.H. 2015. Fixed-dose combinations of renin– angiotensin system inhibitors and calcium channel blockers in the treatment of hypertension. Medicine (Baltimore), 94: 51. https://doi.org/10.1097/MD.000000 0000002355. Hyseni, L., Elliot-Green A., LloydWilliams F., Kypridemos C., O’Flaherty M., McGill R., Orton L., Bromley H., Cappuccio F.P & Capewell S. 2017. Systematic review of dietary salt reduction policies: Evidence for an effectiveness hierarchy? PLOS ONE 18(12):5, e0177535. https://doi.org/10.1371/journal.pone .0177535. Kementerian Kesehatan RI. 2018. Hasil Utama Riset Kesehatan Dasar 2018. Jakarta. Lenfant, F., Trémollières F., Gourdy P. & Arnal, J.F. 2011. Timing of the vascular actions of estrogens in experimental and human studies: Why protective early, and not when delayed?. Maturitas 68(2): 165-173. https://doi.org/10.1016/j.maturitas.2 010.11.016. Li, S. & Gupte A.A. 2017. The Role of Estrogen in cardiac metabolism and diastolic function. Methodist Debakey Cardiovasc J. 13(1): 4-8. https://doi.org/10.14797/mdcj-13-1- 4. Machado, M.A.A., de Moura C.S., Wang Y., Danieli C., Abrahamowicz M., Bernatsky S., Behlouli H & Pilote L. 2017. Comparative effectiveness of antihypertensive drugs in nondiabetic patients with hypertension: A population-based study. The Journal of Clinical Hypertension 19(10): 999-1009. https://doi.org/10.1111/jch.13055. Mubin, M., Samiasih A & Hermawati T. 2010. Karakteristik dan pengetahuan pasien dengan motivasi melakukan kontrol tekanan darah di wilayah kerja Puskesmas Sragi 1 Pekalongan. Jurnal Universitas Muhammadiyah Semarang, 6(2). Pour, E., Aliyari S., Farsi Z., Ghelich Y. 2020. Comparing the effects of interactive and noninteractive education using short message service on treatment adherence and blood pressure among patients with hypertension. Nurs Midwifery Stud, 9(2): 68. https://doi.org/10.4103/nms.nms_82 _19. Rajpura, J. & Nayak R. 2014. Medication Adherence in a Sample of Elderly Suffering from Hypertension: Evaluating the Influence of Illness Perceptions, Treatment Beliefs, and Illness Burden. Journal of Manage Care and Pharm, 20(1): 58-65. https://doi.org/10.18553/jmcp.2014. 20.1.58. Riani, D.A., Ikawati Z., Kristina S.A. 2017. Validasi 8-Item Morisky Medication Adherence Scale Versi Indonesia Pada Pasien Hipertensi Dewasa di Puskesmas Kabupaten Sleman dan Kota Yogyakarta. Tesis Magister Farmasi. Universitas Sanata Darma. Yogyakarta. Rincon-Choles, H. 2019. ACE inhibitor and ARB therapy: Practical Efek Edukasi….(Oktaviani E.., dkk) 75 recommendations. Cleveland Clinic journal of Medicine, 86: 609. Rosyida, L., 2015. Kepatuhan Pasien Pada Penggunaan Obat Antidiabetes Dengan Metode Pill Count dan MMAS-8 di Puskesmas Kedurus Surabaya Selatan. Tesis Doktor. . Universitas Airlangga. Surabaya. Strauss, M.H. & Hall A.S. 2017. Angiotensin receptor blockers do not reduce risk of myocardial infarction, cardiovascular death, or total mortality: further evidence for the ARB-MI paradox. Circulation, 135(22): 2088–2090. Supardi, S., Herman M.J & Susyanty A.L. 2011. Kebijakan Penempatan Apoteker Sebagai Pengelola Obat Di Puskesmas. Pusat Teknologi Intervensi Kesehatan Masyarakat, Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Jakarta. Swandari, M.T.K., Puspitasari I., Kusharwanti A.W. 2014. Evaluasi pengaruh konseling farmasis terhadap kepatuhan dan hasil terapi pasien hipertensi di poliklinik penyakit dalam RSUD Cilacap periode Desember 2013-Januari 2014. Jurnal Manajemen dan Pelayanan Farmasi (Journal of Management and Pharmacy Practice) 4: 219-229. Tarhouni, K., Guihot A.L, Vessières E., Toutain B., Procaccio V., Grimaud L., Loufrani L., Lenfant F., Arnal J.F & Henrion D. 2014. Determinants of flow-mediated outward remodeling in female rodents. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(6): 1281-1289. https://doi.org/10.1161/ATVBAHA .114.303404. Uchmanowicz, B., Chudiak A., Uchmanowicz I., RosiÅ„czuk J., Froelicher E.S. 2018. Factors influencing adherence to treatment in older adults with hypertension. Clin Interv Aging, 13: 2425–2441. https://doi.org/10.2147/CIA.S18288 1. Ukpabi, O.J. & Ewelike, I.D. 2017. The eighth joint national committee on the prevention, detection, evaluation, and treatment of high blood pressure (joint national committee-8) report: Matters arising. Nigerian Journal of Cardiology, 14(1): 15-18. Wang, W.T., You L.K., Chiang C.E., Sung S.H., Chuang S.Y., Cheng H.M., Chen & C.H. 2016. Comparative effectiveness of blood pressure-lowering drugs in patients who have already suffered from stroke. Medicine (Baltimore), 95(15): e3302. https://doi.org/10.1097/MD.000000 0000003302. WHO. 2003. Adherence to long-term therapies: evidence for action. World Health Organization. Geneva. You, S.C., Jung S., Swerdel J.N., Ryan P.B., Schuemie M.J., Suchard M.A., Lee S., Cho J., Hripcsak G., Park R.W & Park S. 2020. Comparison of first-line dual combination treatments in hypertension: real-world evidence from multinational heterogeneous Cohorts. Korean Circulation Journal, 50(1): 52-68. https://doi.org/10.4070/kcj.2019.01 73.

URL : https://journal.unpak.ac.id/index.php/fitofarmaka/article/view/2060/pdf

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Detail Karya Ilmiah Dosen

Emy Oktaviani, Oktaviana Zunnita, Marlia Handayani

Judul	:	EFEK EDUKASI MELALUI BROSUR TERHADAP KONTROL TEKANAN DARAH DAN KEPATUHAN PASIEN HIPERTENSI
Abstrak	:	Adherence is one of the main supporting factors of achieving the therapeutic effect of hypertension treatment. Non-adherence can increase morbidity, mortality, and treatment costs. This study aims to determine the effect of education through brochures on blood pressure control and medication adherence to hypertension. The design of this study is a quasi experimental one group pretest and posttest design prospectively. This study was conducted using respondents of hypertension patients at the Babakan Madang Community Health Center which met the inclusion criteria. Pretest and posttest data collection using MMAS-8 questionnaire and patient medical records. People who are willing to take part in this study are marked by informed consent. The study was conducted by filling out the MMAS-8 questionnaire by interview, blood pressure, and Fitofarmaka Jurnal Ilmiah Farmasi 66 continued with an intervention in the form of education through a brochure. One month later the MMAS-8 questionnaire was filled out with re-interviews and blood pressure measurements. From 50 respondents showed that education through the brochure had an effect on blood pressure control and respondent compliance with the results of statistical tests using the Wilcoxon Signed Rank Test (p<0,05). Keywords: Adherence, blood pressure, brochure, hypertension
Tahun	:	2020	Media Publikasi	:	Jurnal Nasional Terakreditasi A
Kategori	:	Jurnal	No/Vol/Tahun	:	1 / 10 / 2020
ISSN/ISBN	:	2622-755X
PTN/S	:	Universitas Pakuan	Program Studi	:	FARMASI
Bibliography	:	Ayodapo, A., Elegbede O., Omosanya, O & Monsudi K. 2020. Patient education and medication adherence among hypertensives in a tertiary hospital, South Western Nigeria. Ethiop J Health Sci, 30: 243-250. https://doi.org/10.4314/ejhs.v30i2.1 2. Bijani, M., Tehranineshat B., Ahrari F & Beygi N. 2020. A Comparison between Multimedia and traditional education in encouraging adherence to treatment regimen in patients with hypertension. The Open Hypertention Journal, 12: 1-6. https://doi.org/10.2174/1876526202 012010001. Burnier, M. 2017. Drug adherence in hypertension. Pharmacological Research, 125: 142-149. https://doi.org/10.1016/j.phrs.2017. 08.015. Dewanti, S.W., Andrajati R & Supardi S. 2015. Pengaruh konseling dan leaflet terhadap efikasi diri, kepatuhan minum obat, dan tekanan darah pasien hipertensi di dua puskesmas Kota Depok. Jurnal Kefarmasian Indonesia, 5: 33-40. Egan, B.M., Bandyopadhyay D., Shaftman S.R., Wagner C.S., Zhao Y & Yu-Isenberg K.S. 2012. Initial monotherapy and combination therapy and hypertension control the first year. Hypertension, 59: 1124-1131. https://doi.org/10.1161/HYPERTEN SIONAHA.112.194167. Gaffari-fam, S., Babazadeh T., Oliaei S., Behboodi L & Daemi A. 2020. Adherence to a health literacy and healthy lifestyle with improved blood pressure control in Iran. Patient Prefer Adherence, 14: 499- 506. https://doi.org/10.2147/PPA.S2448 20. Gaziano, T.A., Bertram M., Tollman S.M & Hofman K.J. 2014. Hypertension education and adherence in South Africa: a cost-effectiveness analysis of community health workers. BMC Public Health 14, 240. https://doi.org/10.1186/1471-2458- 14-240. Gellad, W.F., Grenard J.L & Marcum Z.A. 2011. A Systematic Review of Barriers to Medication Adherence in the Elderly: Looking Beyond Cost and Regimen Complexity. The American Journal of Geriatric Pharmacotherapy 9, 11–23. https://doi.org/10.1016/j.amjopharm .2011.02.004. Hill, M.N., Miller N.H & DeGeest S. 2011a. Adherence and persistence with taking medication to control high blood pressure. Journal of the American Society of Hypertension 5, 56–63. https://doi.org/10.1016/j.jash.2011. 01.001. Hill, M.N., Miller N.H. & DeGeest S. 2011b. Adherence and persistence Fitofarmaka Jurnal Ilmiah Farmasi 74 with taking medication to control high blood pressure. Journal of the American Society of Hypertension, 5, 56–63. https://doi.org/10.1016/j.jash.2011. 01.001. Hsiao, F.C., Tung Y.C., Chou S.H., Wu L.S., Lin C.P., Wang C.L., Lin Y.S., Chang C.J & Chu P.H. 2015. Fixed-dose combinations of renin– angiotensin system inhibitors and calcium channel blockers in the treatment of hypertension. Medicine (Baltimore), 94: 51. https://doi.org/10.1097/MD.000000 0000002355. Hyseni, L., Elliot-Green A., LloydWilliams F., Kypridemos C., O’Flaherty M., McGill R., Orton L., Bromley H., Cappuccio F.P & Capewell S. 2017. Systematic review of dietary salt reduction policies: Evidence for an effectiveness hierarchy? PLOS ONE 18(12):5, e0177535. https://doi.org/10.1371/journal.pone .0177535. Kementerian Kesehatan RI. 2018. Hasil Utama Riset Kesehatan Dasar 2018. Jakarta. Lenfant, F., Trémollières F., Gourdy P. & Arnal, J.F. 2011. Timing of the vascular actions of estrogens in experimental and human studies: Why protective early, and not when delayed?. Maturitas 68(2): 165-173. https://doi.org/10.1016/j.maturitas.2 010.11.016. Li, S. & Gupte A.A. 2017. The Role of Estrogen in cardiac metabolism and diastolic function. Methodist Debakey Cardiovasc J. 13(1): 4-8. https://doi.org/10.14797/mdcj-13-1- 4. Machado, M.A.A., de Moura C.S., Wang Y., Danieli C., Abrahamowicz M., Bernatsky S., Behlouli H & Pilote L. 2017. Comparative effectiveness of antihypertensive drugs in nondiabetic patients with hypertension: A population-based study. The Journal of Clinical Hypertension 19(10): 999-1009. https://doi.org/10.1111/jch.13055. Mubin, M., Samiasih A & Hermawati T. 2010. Karakteristik dan pengetahuan pasien dengan motivasi melakukan kontrol tekanan darah di wilayah kerja Puskesmas Sragi 1 Pekalongan. Jurnal Universitas Muhammadiyah Semarang, 6(2). Pour, E., Aliyari S., Farsi Z., Ghelich Y. 2020. Comparing the effects of interactive and noninteractive education using short message service on treatment adherence and blood pressure among patients with hypertension. Nurs Midwifery Stud, 9(2): 68. https://doi.org/10.4103/nms.nms_82 _19. Rajpura, J. & Nayak R. 2014. Medication Adherence in a Sample of Elderly Suffering from Hypertension: Evaluating the Influence of Illness Perceptions, Treatment Beliefs, and Illness Burden. Journal of Manage Care and Pharm, 20(1): 58-65. https://doi.org/10.18553/jmcp.2014. 20.1.58. Riani, D.A., Ikawati Z., Kristina S.A. 2017. Validasi 8-Item Morisky Medication Adherence Scale Versi Indonesia Pada Pasien Hipertensi Dewasa di Puskesmas Kabupaten Sleman dan Kota Yogyakarta. Tesis Magister Farmasi. Universitas Sanata Darma. Yogyakarta. Rincon-Choles, H. 2019. ACE inhibitor and ARB therapy: Practical Efek Edukasi….(Oktaviani E.., dkk) 75 recommendations. Cleveland Clinic journal of Medicine, 86: 609. Rosyida, L., 2015. Kepatuhan Pasien Pada Penggunaan Obat Antidiabetes Dengan Metode Pill Count dan MMAS-8 di Puskesmas Kedurus Surabaya Selatan. Tesis Doktor. . Universitas Airlangga. Surabaya. Strauss, M.H. & Hall A.S. 2017. Angiotensin receptor blockers do not reduce risk of myocardial infarction, cardiovascular death, or total mortality: further evidence for the ARB-MI paradox. Circulation, 135(22): 2088–2090. Supardi, S., Herman M.J & Susyanty A.L. 2011. Kebijakan Penempatan Apoteker Sebagai Pengelola Obat Di Puskesmas. Pusat Teknologi Intervensi Kesehatan Masyarakat, Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Jakarta. Swandari, M.T.K., Puspitasari I., Kusharwanti A.W. 2014. Evaluasi pengaruh konseling farmasis terhadap kepatuhan dan hasil terapi pasien hipertensi di poliklinik penyakit dalam RSUD Cilacap periode Desember 2013-Januari 2014. Jurnal Manajemen dan Pelayanan Farmasi (Journal of Management and Pharmacy Practice) 4: 219-229. Tarhouni, K., Guihot A.L, Vessières E., Toutain B., Procaccio V., Grimaud L., Loufrani L., Lenfant F., Arnal J.F & Henrion D. 2014. Determinants of flow-mediated outward remodeling in female rodents. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(6): 1281-1289. https://doi.org/10.1161/ATVBAHA .114.303404. Uchmanowicz, B., Chudiak A., Uchmanowicz I., RosiÅ„czuk J., Froelicher E.S. 2018. Factors influencing adherence to treatment in older adults with hypertension. Clin Interv Aging, 13: 2425–2441. https://doi.org/10.2147/CIA.S18288 1. Ukpabi, O.J. & Ewelike, I.D. 2017. The eighth joint national committee on the prevention, detection, evaluation, and treatment of high blood pressure (joint national committee-8) report: Matters arising. Nigerian Journal of Cardiology, 14(1): 15-18. Wang, W.T., You L.K., Chiang C.E., Sung S.H., Chuang S.Y., Cheng H.M., Chen & C.H. 2016. Comparative effectiveness of blood pressure-lowering drugs in patients who have already suffered from stroke. Medicine (Baltimore), 95(15): e3302. https://doi.org/10.1097/MD.000000 0000003302. WHO. 2003. Adherence to long-term therapies: evidence for action. World Health Organization. Geneva. You, S.C., Jung S., Swerdel J.N., Ryan P.B., Schuemie M.J., Suchard M.A., Lee S., Cho J., Hripcsak G., Park R.W & Park S. 2020. Comparison of first-line dual combination treatments in hypertension: real-world evidence from multinational heterogeneous Cohorts. Korean Circulation Journal, 50(1): 52-68. https://doi.org/10.4070/kcj.2019.01 73.
URL	:	https://journal.unpak.ac.id/index.php/fitofarmaka/article/view/2060/pdf